ROBOX and CarbaZymes are pleased to invite you to explore the state of the art in industrial biocatalysis through the new technologies developed in the EU Horizon 2020 projects ROBOX and CARBAZYMES.

DO NOT MISS IT. Click on the banner to register.

Preliminary programme:

10:00 Welcome and Introduction to the workshop

10:10 Introduction to ROBOX

10:20 Engineering oxidative enzymes
10:40 Producing oxidative enzymes
11:00 Industrial applications of P450 monooxygenases and Baeyer-Villiger monooxygenases
11:40 Industrial applications of alcohol dehydrogenases

12:20 Lunch & Posters

14:20 Introduction to Carbazymes

14:30 Discovery & engineering C-C bond forming enzymes
14:50 Producing Carbazymes Enzymes
15:10 Industrial applications of C-C bond forming enzymes – 1
15:50 Industrial applications of C-C bond forming enzymes – 2

16:30 Close followed by, Networking Reception

This free event will be held at DECHEMA, Max Buchner Lecture Hall in Frankfurt:

DECHEMA, Max Buchner Lecture Hall
Theodor-Heuss-Allee 25,
60486 Frankfurt am Main,




6th NovelEnzymes
October 9 – 12, 2018
Darmstadt, Germany


The 6th Novel Enzymes conference will take place at the Technische Universitaet Darmstadt, Germany, in the old "Maschinenhaus“ from 9 – 12 October 2018.

The main topics of the conference series are current developments in catalysis research using enzymes. Enzymes are natural biocatalysts that enable energy-efficient and environmentally friendly transformations of chemical compounds, thus enabling the development of sustainable production processes for the chemical and pharmaceutical industries. Applied biocatalysis in biotechnology, which is viewed as a key technology for the 21st century, has a high potential for improving the quality of human life and for a global societal impact. Biocatalyis will facilitate the shift from fossil resources towards a low-carbon economy, thus securing the material supply for future generations.

The Novel Enzymes conference brings together more than 200 leading scientists from universities, research institutes and the industry to share their latest findings and developments in the discovery and engineering of novel enzymes. The conference is organized by Wolf-Dieter Fessner, Professor of Bio-Organic Chemistry at the Department of Chemistry of the TU Darmstadt. Emphasizing the highly topical significance of this conference, he said: "The awarding of the Nobel Prize for Chemistry 2018 to the US American scientist Frances Arnold from the California Institute of Technology for her development of groundbreaking methods in creating novel and improved enzymes, is a strong acknowledgment of the great significance of this research area for the future of our planet. Professor Arnold was honored with the Emanuel Merck Lectureship Award in 2013, presented jointly with Merck at the TU Darmstadt. We are extremely pleased for the recognition of her work, which has also significantly benefited our own research.” Professor Fessner is currently coordinating research in two European collaborative projects: CarbaZymes and Tralaminol (14 and 6 partners respectively), which are EU-funded with over 13 million euros, to develop advanced, integrated production processes for the enzyme-catalyzed production of valuable components for active pharmaceutical ingredients, fine chemicals and bulk materials. The Novel Enzymes conference is an important platform to present and discuss the recent results of these projects with experts in the biocatalysis field.

For further information:

Following their successful and fun learning activities at the “Science in the City” Festival in Toulouse, Universidad Autónoma de Madrid (UAM) has been invited to the “European Night of Researchers” in Zaragoza, on Sept 28th 2018.
This will be another great opportunity to demonstrate to the public exciting research conducted within the EU funded innovative biotechnology projects CarbaZymes and MetaFluidics, in which UAM is an active partner.
Everyone is welcome to learn about and test those superpowers!

This research work was also presented as a poster at the Spanish Society for Microbiology conference on Teaching and Dissemination of Microbiology in Madrid in July, where it was awarded first prize. Jorge Bravo, MSc received the prize on behalf of CarbaZymes, MetaFluidics and UAM (pictured).

You can download the winning poster here: Available in English and in Spanish.


Our partner Enzymicals will be present at the CPhI Worldwide in Madrid next October 9th to 11th

CPhI Worldwide, together with co-located events ICSE, InnoPack, P-MEC and FDF, hosts more than 45,000 visiting pharma professionals over three days. 2,500+ exhibitors from 153 countries gather at the event to network and take advantage of more than 150 free industry seminars.

Enzymicals is please to invite you to visit their stand No 3J16 at CPHI.

See you in Madrid.

Since 2002 the International Congress on Biocatalysis (BIOCAT) has been organized as a biennial congress, focused on the rapidly evolving fields of biocatalysis and industrial biotechnology. In August 26 to 30 2018 its 9th edition will be hosted in  Hamburg, Germany. The appeal and impact of Biocat is very significant for the biocatalysis community: for example the 2016 edition attracted more than 2900 participants from over 40 countries.

The major topics to be addressed this year are:

  • Enzyme discovery, production and application
  • Structure-function analysis and enzyme design
  • Enzymatic and whole cell biotransformations
  • Bioprocess engineering and downstream processing
  • Sustainable industrial processes, biorefinery and bioeconomy

The conference´s topics are very much in line with the objectives of CarbaZymes project!

Therefore click here if you don't want to miss it! 


August 27th 2018

14:30–16:30       Poster session 1 – Topic 3: Enzymatic and whole cell biotransformations
Room H0.01-H0.09         

  • P3-2:  Aldol additions of pyruvate analogs to formaldehyde: synthesis of optically active β-hydroxycarboxylic esters.
                Karel Hernández (CSIC).
  • P3-9:  Model optimization of DERA-catalyzed double aldol addition.
                Ana Vrsalović Presečki (UZAG).
  • P3-31: Mathematical modeling of DERA-catalyzed statin side-chain intermediate production.
                  Anera Švarc (UZAG).

August 29th 2018

14:30–16:30       Poster session 3: Structure-function analysis and enzyme design                            
                           Room H0.01-H0.09         

  • P2-28  Thermostabilization of a new halohydrin dehalogenase by protein engineering.            
                 Julia Koopmeiners (TUBS).
  • P2-22  Thermostabilization of the pyruvate aldolase YfaU using an enhanced folding reporter
    Sandra Bosch (UAM)

14:30–16:30       Poster session 3: Bioprocess engineering and downstream processing
Room H0.01-H0.09         

  • P4-14  Scale-up of a novel aldolase approach to produce statin side chain API intermediate.
                 Melinda Fekete (ENZ).

August 30th 2018

Industrial implementations, Morning session 5 – Topic 3: Enzymatic and whole cell biotransformations (Room Audimax I)

11:20–11:40       L3-8      Selective ring-opening of di-substituted epoxides by halohydrin dehalogenases. 
                                            Anett Schallmey (TUBS).

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