The Technische Universitaet Darmstadt is one of the leading universities of technology in Germany and has earned international visibility and renown. Its outstanding scientific performance has been recognized by multiple grants within the German Excellence Initiative and European FP7 and Horizon 2020 grants.

Technology is at the heart of all disciplines at TUDA, and the natural sciences cooperate closely with engineering.

TUDA link: http://www.tu-darmstadt.de/index.en.jsp

Role in the project

TUDA, on one hand, as the Coordinator of the project, will monitor the timely implementation of the work packages, record the accomplishments of the CARBAZYMES project and interact with both the European Commission and the stakeholders on behalf of the Consortium.

On the other hand, due to its extensive experience in the field of applied biocatalysis for asymmetric synthesis in general, TUDA will be well involved in WP2, reaction optimization,  WP4 bioprocess development and WP5, scale-up and demonstration The design, execution and optimization of enzyme catalysis on exploratory and on a larger laboratory scale  will also be implemented at TUDA.

More specifically, TUDA will undertake the engineering of aldolases using rational design and in vitro evolution, as well as the optimization of reaction systems for improved product yield and selectivity using engineered enzymes.

Contributors to the CARBAZYMES

Prof. Fessner´s Group link: http://www.chemie.tu-darmstadt.de/fessner/agfessner/start_1.en.jsp

 Prof. Dr. Wolf-Dieter Fessner

 Project Coordinator and Principal Investigator

 Dr. Anders Magnusson

 Postdoctoral Researcher

 Dr. Anna Szekrenyi

 Postdoctoral Researcher

 Ms. Agapi Theodoridou

 Project Manager

 Mr. Michael Kickstein

 Laboratory Technician

 Ms. Serbet Pinar-Safi

 Administrative Assistant

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